AlphaRose Therapeutics

Scaling Precision Genetic Medicine Globally
Austin

About AlphaRose Therapeutics

AlphaRose Therapeutics was started by Casey McPherson, a critically acclaimed musician, when his daughter Rose was diagnosed with a rare genetic disease with no cure. McPherson spent years putting a team and science together to change the broken healthcare system for children like his daughter. AlphaRose is a new business and technology model, changing the way we develop and commercialize genetic medicines. Starting with their Antisense Oligonucleotide platform, and focusing on children with severe neurological diseases, AlphaRose plans on rapidly developing hundreds of genetic treatments for small population diseases at scale. The companies' lead product, "Rosiphersen" is slated for clinic in early 2026, and has a large pipeline of additional assets.

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Problem statement

Drug development is slow, expensive, and often times the end result is a molecule that only works for a subpopulation of patients. Genetics are showing us that the most impactful drugs target the root cause of a disease, following the unique biology of a patient or acute patient population, but the pharma business model has no interest in scaling thousands of treatments for thousands of small diseases. If we don't change our way of thinking, it has been said it will take a thousand years to treat genetic disease, and billions of lives will be lost. AlphaRose can change that.

Traction information

- Alpha Rose has raised 2.1m
The Company is co-founded by executives from the infamous Genzyme Corporation, and collectively has commercialized over 20 rare disease products globally.
- They in-licensed Rosiphersen which is slated for clinic in 2026, with an expected peak annual revenue of 700m.
- The AI platform they are developing has already identified 300+ diseases that are potentially amenable to their technology platform.
- AlphaRose has acquired a new ASO technology, giving it the ability to out license, and co-develop treatments.

Milestones

January 2025

Started Reg Cf Round

We completed due diligence and began launch of our Reg CF Round for 5m. www.startengine.com/alpharose

August 2024

Completed Stage 1 of Argus Ai

We completed our genetic graph database and initial algorithms to identify amenable genetic mutations.

July 2024

In-Licensed Rosiphersen

We succesfuly in licensed our lead product, “Rosiphersen” into AlphaRose Therpauetics from our partner “The To Cure A Rose Foundation.”

March 2024

Capitalized Company

Our Company launch with initial pre-seed capital from the Termeer Family Office.

February 2024

Established all Partners for Clinical Trial of Rosiphersen

All contracts, quotes, and plans assembled for manufacturing, fill and finish, regulatory and clinical partners for lead product, “Rosiphersen.”

Updates

Profile created.
Added 3 days ago

Funding

Not raising capital right now

$1,200,000
committed
$5,000,000
round goal
Total raised to date:$2,200,000
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