ClearSight Therapeutics, Inc.

Innovation in Sight
Dallas

About ClearSight Therapeutics, Inc.

ClearSight Therapeutics is dedicated to enhancing patient outcomes by developing innovative over-the-counter (OTC) products for individuals suffering from Dry Eye Disease, Contact Lens Rewetting, and Acute Infectious Conjunctivitis (commonly known as “Pink Eye”). We leverage our proprietary dual-action formulation, which combines an artificial tear with a potent antimicrobial biopolymer. Our products will be the first in their class to address biofilm complications associated with Dry Eye and extended contact lens wear. Furthermore, our Pink Eye treatment will be the first OTC medication able to treat viral pink eye, which accounts for approximately 80% of cases.

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Problem statement

ClearSight’s proprietary, patent-pending formulation features a powerful antimicrobial biopolymer that effectively targets and eliminates bacterial, fungal, and viral infections associated with pink eye. Unlike antibiotics, this biopolymer acts on the bacterial cell wall, preventing the development of bacterial resistance. Furthermore, ClearSight’s biopolymer can remove biofilm, which is a challenging complication often seen in Dry Eye Disease and infections related to contact lens use.

Traction Metrics

Traction information

1. Demand Traction - LOI with a Pediatric commercial partner, Cartwheel (fellow Capital Factory All-Access company) for $21M over 5 years. Launch in 2027.
2. Demand Traction - LOI with Eye Care commercial partner, Covalent Medical, for $63M over 5 years. Launch in 2027
3. IP - Composition Pending filled and expect issuance in the next few quarters
4. Earned PR - Excitement building for launch with Cartwheel: D CEO Article on partnership published Jan 2026

Milestones

February 2026

Signed an LOI with Eye Care partner Covalent Medical - $63M over 5 years

Clearsight and Covalent Medical have signed an LOI for $63M over 5years. ClearSight will manufacture and produce 6 unique SKUs for Covalent Medical to commercialize and sell. The agreement will entail 3 products under the Focus Tears brand family (www.focusvitamins.com), which will be sold directly through Ophthalmologists and Optometrists to patients suffering from Dry Eye, Wearing contact lenses and Pink Eye. They will also launch 3 SKUs under a separate brand, Alivyo, for sale through the Retail Channel (CVS, Walgreens, etc.).

October 2025

Signed LOI with Cartwheel - $21M over 5 years

ClearSight will manufacture and provide a private-label version of our innovative over-the-counter (OTC) pink eye treatment. Cartwheel will package and sell this product to major retail chains in the US under its brand. Cartwheel is set to launch its lice treatment in 2026 and will focus on introducing the ClearSight formulation in 2027.

April 2025

Completed key antimicrobial pre-clinical studies

We have finished developing our formulation and conducted pre-clinical tests for antibacterial, antifungal, and antiviral activity. We have also started our key pre-clinical biofilm study and expect to see results soon.

March 2025

Established a partnership with a Contract Development and Manufacturing Organization - Unither Pharmaceuticals.

Established a partnership with Unither Pharma, Rochester, NY, for the development and manufacturing of our clinical and commercial products.

March 2025

Established API partner - Chitolytic

Established a partnership with Chitolytic to supply ClearSight with GMP-quality active pharmaceutical ingredient (API) which is a critical component of our novel ophthalmic solutions.

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Funding

Currently raising capital

$100,000
committed
$1,000,000
round goal
Total raised to date: $350,000
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